Table 4 Associations between exposures and pregnancy outcomes.

From: Examining Reproductive Health Outcomes in Females Exposed to Polychlorinated Biphenyl and Polybrominated Biphenyl

 

Mean (range)

PCB

PBB

\({\boldsymbol{\beta }}\) (95% CI)

P-value

\({\boldsymbol{\beta }}\) (95% CI)

P-value

Number of pregnancies

2.84 (0–10)

−0.11 (−0.21 to −0.005)

0.04

0.02 (−0.06 to 0.09)

0.64

Pregnancy Outcomes

N (%)

OR (95% CI)

P-value

OR (95% CI)

P-value

Singleton live birth (SLB)

369 (82.2%)

0.89 (0.65 to 1.22)

0.47

1.03 (0.83 to 1.26)

0.78

Miscarriage

80 (17.8%)

1.12 (0.82 to 1.52)

0.47

0.97 (0.79 to 1.19)

0.78

SLB Outcomes

N (%)

OR (95% CI)

P-value

OR (95% CI)

P-value

Preterm birtha

35 (9.5%)

0.98 (0.62 to 1.53)

0.93

0.99 (0.73 to 1.34)

0.97

Low birth weightb

23 (6.2%)

1.03 (0.62 to 1.70)

0.91

1.11 (0.77 to 1.61)

0.56

High birth weightc

39 (10.6%)

0.69 (0.43 to 1.12)

0.13

0.96 (0.70 to 1.30)

0.79

Birth defects

26 (7.0%)

0.93 (0.55 to 1.55)

0.78

0.86 (0.61 to 1.22)

0.40

Hypertensive disorders of pregnancyd

29 (7.9%)

1.49 (0.87 to 2.53)

0.14

1.29 (0.83 to 2.02)

0.25

Gestational diabetes

25 (6.8%)

1.06 (0.59to 1.87)

0.85

0.96 (0.56 to 1.67)

0.90

 

Mean (range)

\({\boldsymbol{\beta }}\) (95% CI)

P-value

\({\boldsymbol{\beta }}\) (95% CI)

P-value

Birth weight (grams)

3351 g (1219–5415 g)

−65.2 (−160.5 to 30.1)

0.18

30.9 (−30.0 to 91.9)

0.32

  1. Adjusted for age (current age & age at pregnancy), BMI, and total lipid levels. Total PCB levels adjusted for total PBB and total PBB levels adjusted for total PCB. OR = odds ratio. CI = confidence interval.
  2. Bold indicates statistically significant values with p-value of <0.05.
  3. a < 37 weeks gestational age.
  4. bSelf-reported birth weight <2500 g.
  5. cSelf-reported birth weight >4000 g.
  6. dGestational hypertension, preeclampsia, or eclampsia.
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