Table 4 Validation of P-Net patients’ ranking using a non parametric test on the different datasets. Results of the random label permutation test to assess the significance of patients ranking. RWK stands for Random Walk Kernel, Diff. score for Differential score, Dnorm score for Differential normalized score. For the Pancreatic cancer dataset, results with different training set sizes are shown.

From: Network modeling of patients' biomolecular profiles for clinical phenotype/outcome prediction

Dataset

P-Net methods

p-value (ranking)

Pancreatic - 16 patients

RWK8, NN score

0.0010

Pancreatic - 18 patients

RWK8, NN score

0.0060

Pancreatic - 20 patients

RWK8, NN score

0.0120

Pancreatic - 24 patients

RWK8, NN score

0.0060

Pancreatic - 28 patients

RWK8, NN score

0.0170

Breast

RWK1, Dnorm score

0.0000

Colorectal

RWK1, Diff. score

0.0490

Colon

RWK1, Diff. score

0.0440