Figure 5
From: Characterization of a Species E Adenovirus Vector as a Zika virus vaccine
Antibody and T-cell response after vaccination with Adenovirus 4 or 5 expressing an influenza hemagglutinin transgene. (A,B) C57BL/6 mice (n = 5) were vaccinated with an Adenovirus 4 or 5 vector expressing a consensus hemagglutinin H1 influenza gene. Hemagglutinin (HA) specific antibodies to the H1N1 virus PR/8/34 were measured using an ELISA (A) (n.s. not significant, ****p < 0.0001; one-way ANOVA). The total T-cell response against the HA of A/PR/8/34 was determined with pooled peptides from a peptide array covering the entire HA and are reported as spot forming cells (SFC) per million (B) (*p < 0.05, **p < 0.01, one-way ANOVA). Data are expressed as the mean with standard error (SEM).
