Table 1 Characteristics of the clinical study subjects Group 1 (n = 30).

Body mass index (kg/m²)

36.8 ± 0.9

38.3 ± 1.1

Fasting glucose (mg/dl)

88 ± 1

97 ± 3*

Fasting insulin (µU/ml)

10.2 ± 0.8

24.9 ± 3.3*

Glucose infusion rate during the HECP (µmol/kg FFM/min)

44.8 ± 3.7

26.7 ± 1.8*

Baseline

After weight loss

Body mass index (kg/m²)

39.7 ± 1.8

31.7 ± 1.4^†

Fasting glucose (mg/dl)

90 ± 2

85 ± 2^†

Fasting insulin (µU/ml)

19.2 ± 2.3

7.9 ± 0.8^†

Glucose infusion rate during the HECP (µmol/kg FFM/min)

48.3 ± 6.5

65.2 ± 5.1^†

Baseline

After weight gain

Body mass index (kg/m²)

35.4 ± 1.6

37.5 ± 1.7^†

Fasting glucose (mg/dl)

106 ± 3

111 ± 5

Fasting insulin (µU/ml)

28.3 ± 4.8

32.7 ± 7.3

Glucose infusion rate during the HECP (µmol/kg FFM/min)

29.6 ± 5.4

24.9 ± 4.3^†