Figure 4

Decline of sinusoidal circulation post K/X treatment. (A) DCE-MRI was performed prior to and post K/X treatment at 3 h (n = 6). (B) Illustration of the Ktrans map of a mouse (mouse#3) prior to and post K/X treatment at 3 h. (C) Corresponding circulation in hepatic sinusoids was identified by autofluorescence signal of Evan’s blue. Magnification: 400× and scale bar: 50 um.