Figure 3 | Scientific Reports

Figure 3

From: Clinical significance of circulating soluble immune checkpoint proteins in sorafenib-treated patients with advanced hepatocellular carcinoma

Figure 3

Relationship between fold-changes in soluble immune checkpoint protein levels at 2 weeks of treatment. Significant positive correlation between fold-change in (a) sCTLA-4 and sBTLA; (b) sCTLA-4 and sPD-1, and sCTLA-4 and sPD-L1; (c) sCTLA-4, sCD80, and sCD86 with each other; (d) sPD-1 and sPD-L1. Spearman’s rank correlation test was used. A p value of <0.05 was considered statistically significant.

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