Figure 5
From: Leucine-rich alpha 2 glycoprotein is a new marker for active disease of tuberculosis
LRG levels in the lung tissue and sera of patients with tuberculosis. (A) Localization of LRG in the lung lesion of a patient with tuberculosis. Paraffin section of the lung was obtained from a patient with TB. LRG was visualized by immunohistochemical staining. CN (caseous necrosis). Bar = 200 μm (B) Serum LRG levels in tuberculosis patients (n = 86) and healthy volunteers (n = 31) were determined by ELISA. Data are presented as Tukey’s boxplots (median, upper and lower quartiles). *p < 0.001, by t-test. Blood samples were obtained from patients (n = 23) with active tuberculosis before and 1 month after starting a standard anti-tuberculosis therapy. Levels of LRG in these TB patients were determined by ELISA. *p < 0.001, by paired t-test.
