Table 2 Encapsulation efficacy (ee), drug loading (dl), activity per mg pPAL, and maintained activity compared to free pPAL of pPAL in MSP-l at different PAL/MSP mass ratios. Data represent the mean ± SD (n = 3).

From: A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study

PAL/MSP [w/w]

ee [%]

dl [%]

Activity [IU/mgPAL]

Activity [%]

1:10

41.8 ± 8.9

4.8 ± 2.2

0.95 ± 0.33

79.9 ± 35.1

2:10

36.6 ± 9.0

7.9 ± 1.3

0.81 ± 0.10

67.8 ± 16.5

4:10

41.4 ± 2.5

18.5 ± 4.1

0.54 ± 0.16

43.8 ± 10.7

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