Figure 3

WBP5^high and WBP5^low subgroups have distinct global gene expression profiles. (A) Hierarchical clustering of the Pearson correlation coefficient of mRNA expression showing distinct clusters for high and low WBP5 expressers from the Verhaak cohort. The mutational status of every patient is indicated by a colour coded graph on the top of the clustering map. A legend indicating each genetic subgroup is placed below the clustering map. (B) Heatmap indicating the gene expression profiles of WBP5^low and WBP5^high subgroups. (C) Hierarchical clustering of the Pearson correlation coefficient and (D) heatmap of mRNA values from the WBP5^low and WBP5^high subgroups of the patient cohort reported by Kohlmann et al. The cluster of low and high WBP5 expressers are indicated with blue and red boxes, respectively.