Table 1 Genetic and karyotypic characteristics of the WBP5high and WBP5low patient subgroups.

From: High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia

 

WBP5low (n = 160)

WBP5hi (n = 72)

p-value

Molecular abnormalities

IDH1

7

4

0.74231192

IDH2

5

6

0.10035424

NPM1c

24

31

8.95E-06

FLT3-ITD

22

29

1.38E-05

FLT3-TKD

17

7

1

NRAS

22

4

0.07474453

KRAS

4

0

0.31345029

EVI1

2

11

6.37E-05

CEBPA

18

0

0.00112984

Karyotypic abnormalities

+8

10

4

1

−5/7q

6

10

0.00925701

−9q

5

0

0.32772068

11q23

5

3

0.70598866

complex

8

0

0.06052875

NN

50

31

0.10135058

Other

14

9

0.47627351

abn(3q)

0

1

1

failure

1

4

0.03330118

idt(16)

23

1

0.00180154

t(15;17)

1

0

0.1433

t(6;9)

0

1

0.31034483

t(8;21)

32

0

4.68E-06

t(9;22)

1

0

1

FAB classification

M0

8

3

1

M1

25

27

0.00054777

M2

39

20

0.62606826

M4

36

8

0.04664368

M5

39

8

0.0216892

M6

0

1

0.31034483

unknown

3

0

0.55419693

Sex

Male

80

31

0.39421991

Female

80

41

0.39421991

  1. The table shows data for the 232 patients from the Verhaak dataset (GSE6891), including the occurrence of common karyotypic lesions and molecular aberrations, FAB classification and sex of patients.
Back to article page