Table 1 Baseline characteristics of patients admitted for ACS at the GULF-COAST, with a LVEF > = 40%, according to beta-blockers on admission.
Variable | Beta-blockers on admission N = 1123 (55.4%) | No beta-blockers on admission N = 905 (44.5%) | P value |
|---|---|---|---|
Demographics | |||
Age (years) | 62.3 ± 11.6 | 61.2 ± 11.9 | 0.08 |
Gender (Male) | 470 (59.6%) | 376 (59.3%) | 0.92 |
BMI (kg/m2) | 29.7 ± 9.5 | 29.7 ± 6.5 | 0.94 |
Smoking (current) | 137 (17.4%) | 142 (22.4%) | 0.017 |
Past medical history | |||
Dyslipidemia | 595 (75.4%) | 393 (62.0%) | <0.001 |
Hypertension | 692 (87.7%) | 500 (78.9%) | <0.001 |
Diabetes | 491 (62.2%) | 396 (62.5%) | 0.92 |
Myocardial infarction | 290 (36.8%) | 88 (13.9%) | <0.001 |
Stroke/TIAs | 66 (8.4%) | 50 (7.9%) | 0.46 |
PAD | 25 (3.2%) | 15 (2.4%) | 0.36 |
Cancer | 9 (1.1%) | 9 (1.4%) | 0.64 |
Venous thrombo-embolism | 3 (0.4%) | 5 (0.8%) | 0.47 |
CKD | 79 (10.0%) | 37 (5.8%) | 0.004 |
Clinical parameters | |||
SBP, mmHg, mean ± SD | 144.2 ± 28.5 | 145.0 ± 26.4 | 0.58 |
DBP, mmHg, mean ± SD | 80.0 ± 16.0 | 82.1 ± 15.7 | 0.01 |
HR, bpm, mean ± SD | 82.9 ± 20.0 | 86.9 ± 21.1 | <0.001 |
LVEF, % | 53.2 ± 8.3 | 53.9 ± 8.4 | 0.11 |
Medications prior to admission | |||
Aspirin | 680 (86.2%) | 385 (60.7%) | <0.001 |
ACE-inhibitors and/or ARBs | 566 (71.7%) | 424 (66.9%) | 0.048 |
Statins | 692 (87.7%) | 419 (66.1%) | <0.001 |
Clopidogrel or prasugrel | 286 (36.2%) | 79 (12.5%) | <0.001 |