Figure 5
From: Chemokine releasing particle implants for trapping circulating prostate cancer cells
Optimization of cancer trap. The efficiency of EPO-loaded and SDF-1α-loaded particles to recruit metastatic KD and parental PC3 Qtracker-labeled cancer cells was evaluated in vivo. (A) After cancer inoculation for 36 hours, whole animal images were taken. (B) The fluorescent intensity at the particle implant sites was quantified. The estimated number of KD cells at EPO and SDF-1α particle implant sites are 67,000 and 53,000 cells per implant, respectively. The estimated PC3 cells at EPO and SDF-1α particle implant sites are 8,960 and 7,750 cells per implant, respectively. N = 3 in all groups. Data are shown as mean ± SD. (Student’s t-test, *p < 0.05).
