Table 1 Details of the RSFCs whose contributions are above 0.5 (27 RSFCs).

From: Alterations of functional connectivities associated with autism spectrum disorder symptom severity: a multi-site study using multivariate pattern analysis

ROI1	Coordinates	BL	Net	ROI2	Coordinates	BL	Net	R	Contribution
Name (BA)	Coordinates	BL	Net	Name (BA)	Coordinates	BL	Net	R	Contribution
Positive RSFCs
Cerebelum_10_L(107)	−22, −33, −41	CRBL10.L	Cerebel	PUT.R(74)	27, 4, 2	Insula	SBN	0.33	1.00
Cerebelum_10_L(107)	−22, −33, −41	CRBL10.L	Cerebel	PUT.L(73)	−23, 3, 2	Insula	SBN	0.3	1.00
SFGmed.R(24)	9, 50, 30	prefrontal	DMN	PoCG.L(57)	−42, −22, 48	Parietal	SMN	0.30^a,b	1.00^c
Cerebelum_10_L(107)	−22, −33, −41	CRBL10.L	Cerebel	PAL.R(76)	21, 0, 0	Insula	SBN	0.29	1.00
HES.L(79)	−41, −18, 9	Temporal	SMN	ANG.R(66)	45, −59, 38	Parietal	EAN	0.27^a	1.00^c
SFGmed.L(23)	−4, 49, 30	prefrontal	DMN	PoCG.L(57)	−42, −22, 48	Parietal	SMN	0.26^a,b	1.00^d
REC.L(27)	−5, 37, −18	prefrontal	DMN	AMYG.L(41)	−23, 0, −17	Temporal	SBN	0.25^b	1.00^d
SFGmed.L(23)	−4, 49, 30	prefrontal	DMN	PreCG.L(1)	−38, −5, 50	Frontal	DMN^*	0.24^b	0.98^d
Negative RSFCs
HES.L(79)	−41, −18, 9	Temporal	SMN	HES.R(80)	45, −17, 10	Temporal	SMN^*	−0.32^a	1.00^c
HES.L(79)	−41, −18, 9	Temporal	SMN	STG.R(82)	58, −21, 6	Temporal	SMN^*	−0.29^a	1.00^c
STG.R(82)	58, −21, 6	Temporal	SMN	STG.L(81)	−53, −20, 7	Temporal	SMN^*	−0.28^a	1.00^c
STG.R(82)	58, −21, 6	Temporal	SMN	ROL.L(17)	−47, −8, 13	Frontal	SMN^*	−0.28^a	1.00^c
HES.R(80)	45, −17, 10	Temporal	SMN	ROL.L(17)	−47, −8, 13	Frontal	SMN^*	−0.27^a	1.00^c
STG.L(81)	−53, −20, 7	Temporal	SMN	HES.R(80)	45, −17, 10	Temporal	SMN^*	−0.27^a	1.00^c
PreCG.L(1)	−38, −5, 50	Frontal	DMN	Vermis_6(112)	1, −67, −15	Vermis6	Cerebel	−0.25^b	1.00
OLF.L(21)	−8, 15, −11	prefrontal	SBN	IOG.R(54)	38, −81, −7	Occipital	Visual	−0.25	1.00^c
HIP.L(37)	−25, −20, −10	Temporal	SBN	PHG.L(39)	−21, −15, −20	Temporal	SBN^*	−0.26	0.99^d
MTG.R(86)	57, −37, −1	Temporal	DMN	ACG.L(31)	−4, 35, 13	Insula	DMN^*	−0.25^b	0.99^c
LING.L(47)	−14, −67, −4	Occipital	Visual	PCL.L(69)	−7, −25, 70	Parietal	SMN	−0.25^a	0.99^d
LING.L(47)	−14, −67, −4	Occipital	Visual	PCL.R(70)	7, −31, 68	Parietal	SMN	−0.25^a	0.99^c
SFGmed.R(24)	9, 50, 30	prefrontal	DMN	MFG.L(7)	−33, 32, 35	prefrontal	EAN	−0.24^b	0.99^c
MTG.L(85)	−55, −33, −2	Temporal	DMN	MFG.L(7)	−33, 32, 35	prefrontal	EAN	−0.24^b	0.98^d
ROL.L(17)	−47, −8, 13	Frontal	SMN	Vermis_3(110)	1, −39, −11	Vermis3	Cerebel	−0.24^a	0.93
MTG.L(85)	−55, −33, −2	Temporal	DMN	ACG.L(31)	−4, 35, 13	Insula	DMN^*	−0.23^b	0.87^d
LING.R(48)	16, −66, −3	Occipital	Visual	PCL.L(69)	−7, −25, 70	Parietal	SMN	−0.24^a	0.85^c
MTG.R(86)	57, −37, −1	Temporal	DMN	MFG.L(7)	−33, 32, 35	prefrontal	EAN	−0.23^b	0.77^c
HIP.L(37)	−25, −20, −10	Temporal	SBN	PHG.R(40)	25, −15, −, −20	Temporal	SBN^*	−0.23	0.64^c

Abbreviations: “BA” indicates the AAL brain area; “.L”, left-hemisphere; “.R”, right-hemisphere; “BL”: brain lobe. “Coordinates” refer to the AAL coordinate. A positive/negative “R” value indicates a positive/negative correlation between the RSFC and the observation score, and |R| > 0.17 corresponds to P < 0.05 (uncorrected). The “Contribution” of the RSFC is calculated as the ratio of the LOOCV folds in which the RSFC was chosen as a feature to all folds. “*” indicates the intra-network RSFCs, and the remaining RSFCs are inter-network. “^a” indicates SMN-related RSFCs. “^b” indicates DMN-related RSFCs. “^c” indicates inter-hemispheric RSFCs (except cerebellum), and “^d” indicates RSFCs within the left hemisphere. DMN, default mode network; SMN, sensorimotor network; SBN, subcortical nuclei regions; EAN, execution and attention network; Visual, visual network; Cerebel, cerebellum.

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Table 1 Details of the RSFCs whose contributions are above 0.5 (27 RSFCs).

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