Table 2 Pathway enrichment analysis of DEGs in IVD cells using GSEA.
Gene Set Name | SIZE | ES | NES | p-val |
|---|---|---|---|---|
Upregulated | ||||
KEGG_VIBRIO_CHOLERAE_INFECTION | 46 | 0.386 | 1.418 | 0.068 |
KEGG_DORSO_VENTRAL_AXIS_FORMATION | 19 | 0.494 | 1.375 | 0.128 |
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | 58 | 0.348 | 1.338 | 0.025 |
KEGG_ERBB_SIGNALING_PATHWAY | 82 | 0.325 | 1.323 | 0.019 |
KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM | 32 | 0.388 | 1.312 | 0.058 |
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 117 | 0.312 | 1.312 | 0.048 |
Downregulated | ||||
KEGG_REGULATION_OF_AUTOPHAGY | 31 | 0.472 | 1.752 | 0.000 |
KEGG_CITRATE_CYCLE_TCA_CYCLE | 29 | 0.401 | 1.515 | 0.000 |
KEGG_JAK_STAT_SIGNALING_PATHWAY | 140 | 0.358 | 1.456 | 0.059 |
KEGG_MISMATCH_REPAIR | 22 | 0.445 | 1.445 | 0.060 |
KEGG_HOMOLOGOUS_RECOMBINATION | 25 | 0.458 | 1.416 | 0.053 |
KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY | 47 | 0.464 | 1.394 | 0.086 |
