Table 5 Diagnostic performance of interpretative criteria for prediction of complete response and progressive disease applied to all primary tumours, all nodal disease, HPV-positive OPC, HPV-negative OPC and Hypopharynx/Larynx sub-groups. Mean values for each diagnostic performance metric across all 4 IC are also provided. () = number of cases provided.
NI-RADS | Porceddu | Hopkins | Deauville | Mean | |
|---|---|---|---|---|---|
All Primary Tumour | |||||
Sensitivity | 47.06 | 55.46 | 52.8 | 52.99 | 52.1 |
Specificity | 98.72 | 95.64 | 95.86 | 96 | 96.6 |
PPV | 92.31 | 82.5 | 82.5 | 82.67 | 85.0 |
NPV | 85.08 | 85.28 | 84.6 | 85.01 | 85.0 |
Accuracy | 85.99 | 84.77 | 84.23 | 84.62 | 84.9 |
All Node | |||||
Sensitivity | 47.37 | 57.43 | 48.33 | 50.91 | 51.0 |
Specificity | 99.04 | 98.93 | 99.09 | 99.07 | 99.0 |
PPV | 93.75 | 95.08 | 95.08 | 94.92 | 94.7 |
NPV | 86.15 | 86.6 | 84.06 | 85.52 | 85.6 |
Accuracy | 87.04 | 87.96 | 85.56 | 86.81 | 86.8 |
All HPV-positive OPC | |||||
Sensitivity | 44.44 | 61.54 | 42.11 | 45.45 | 48.4 |
Specificity | 99.35 | 99.28 | 99.36 | 99.36 | 99.3 |
PPV | 92.31 | 94.12 | 94.12 | 93.75 | 93.6 |
NPV | 91.12 | 93.24 | 87.64 | 89.6 | 90.4 |
Accuracy | 91.21 | 93.33 | 88.21 | 89.95 | 90.7 |
All HPV-negative OPC | |||||
Sensitivity | 61.54 | 64.29 | 56.25 | 60 | 60.5 |
Specificity | 96 | 96 | 96 | 96 | 96.0 |
PPV | 88.89 | 90 | 90 | 90 | 89.7 |
NPV | 82.76 | 82.76 | 77.42 | 80 | 80.7 |
Accuracy | 84.21 | 84.62 | 80.49 | 82.5 | 83.0 |
All Hypopharynx/Larynx | |||||
Sensitivity | 32.14 | 44.12 | 42.86 | 44.12 | 40.8 |
Specificity | 100 (9) | 93.75 | 93.88 | 93.75 | 93.8 |
PPV | 100 (9) | 83.33 | 83.33 | 83.33 | 57.9 |
NPV | 70.31 | 70.31 | 69.7 | 70.31 | 70.2 |
Accuracy | 73.97 | 73.17 | 72.62 | 73.17 | 73.2 |
