Table 5 The proportions of individual variables consisting all or significant syndromes: principal component-based or equal-weight 4-item syndromes.

From: Using syndrome mining with the Health and Retirement Study to identify the deadliest and least deadly frailty syndromes

Most frequent variables in significant syndromes (order, frequencies, proportions relative to significant syndromes, proportions relative to all syndromes)

PC-based syndromes

Equal-weight 4-item syndromes

1

Tiredness all the time (variable name = r7tired)

(i) Felt that everything I did was an effort in last week. (variable name = r7effort)

Frequencies of constituting significant syndromes

1799

54740

Proportions relative to significant syndromes

0.643

0.057

Proportions relative to all syndromes

0.357

0.056

2

Musculoskeletal problems (variable name = r7muscle)

(ii) Could not get going in last week. (variable name = r7going)

Frequencies of constituting significant syndromes

1619

54740

Proportions relative to significant syndromes

0.578

0.057

Proportions relative to all syndromes

0.321

0.056

3

Grip strength, right hand (variable name = r7gripr)

Frequencies of moderate physical activities (variable name = r7mdactx)

Frequencies of constituting significant syndromes

1555

54740

Proportions relative to significant syndromes

0.556

0.057

Proportions relative to all syndromes

0.308

0.056

4

Dummy: Malignant disease (variable name = r7cancrcat)

Frequencies of light physical activities (variable name = r7ltactx)

Frequencies of constituting significant syndromes

1553

54740

Proportions relative to significant syndromes

0.555

0.057

Proportions relative to all syndromes

0.308

0.056

5

Malignant disease (variable name = r7cancr)

Impaired mobility (variable name = r7mobila)

Frequencies of constituting significant syndromes

1519

54740

Proportions relative to significant syndromes

0.543

0.057

Proportions relative to all syndromes

0.301

0.056

Deadly syndromes only

Most frequent variables in deadly syndromes (order, proportions relative to significant syndromes, proportions relative to all syndromes)

PC-based syndromes

Equal-weight 4-item syndromes

1

Tiredness all the time (variable name = r7tired)

(i) Felt that everything I did was an effort in last week. (variable name = r7effort)

Frequencies of constituting significant syndromes

804

54740

Proportions relative to significant syndromes

0.287

0.057

Proportions relative to all syndromes

0.159

0.056

2

Musculoskeletal problems (variable name = r7muscle)

(ii) Could not get going in last week. (variable name = r7going)

Frequencies of constituting significant syndromes

749

54740

Proportions relative to significant syndromes

0.268

0.057

Proportions relative to all syndromes

0.149

0.056

3

Grip strength, right hand (variable name = r7gripr)

Frequencies of moderate physical activities (stratified according to sex) (variable name = r7mdactx)

Frequencies of constituting significant syndromes

704

54740

Proportions relative to significant syndromes

0.252

0.057

Proportions relative to all syndromes

0.14

0.056

4

Malignant disease (variable name = r7cancr)

Frequencies of light physical activities (stratified according to sex) (variable name = r7ltactx)

Frequencies of constituting significant syndromes

697

54740

Proportions relative to significant syndromes

0.249

0.057

Proportions relative to all syndromes

0.138

0.056

5

Dummy: malignant disease (variable name = r7cancrcat)

Impaired mobility (variable name = r7mobila)

Frequencies of constituting significant syndromes

681

54740

Proportions relative to significant syndromes

0.243

0.057

Proportions relative to all syndromes

0.135

0.056

Death-averse syndromes only

Most frequent variables in death-averse syndromes (order, proportions relative to significant syndromes, proportions relative to all syndromes)

PC-based syndromes

Equal-weight 4-item syndromes

1

Tiredness all the time (variable name = r7tired)

History relevant to cognitive impairment or loss (variable name = r7cogtot)

Frequencies of constituting significant syndromes

995

4028

Proportions relative to significant syndromes

0.355

0.004

Proportions relative to all syndromes

0.197

0.004

2

Dummy: Malignant disease (variable name = r7cancrcat)

Body mass index: kg/m2 (variable name = r7bmi)

Frequencies of constituting significant syndromes

872

765

Proportions relative to significant syndromes

0.312

0.001

Proportions relative to all syndromes

0.173

0.001

3

Musculoskeletal problems (variable name = r7muscle)

Grip strength, largest value(variable name = r7grip)

Frequencies of constituting significant syndromes

870

740

Proportions relative to significant syndromes

0.311

0.001

Proportions relative to all syndromes

0.173

0.001

4

Weight in wave 2002 minus weight in wave 2004 !10% of weight in wave 2002 or body mass index o18.5 kg/m2 (variable name = r7frail1_2)

Weight in kilograms (variable name = r7weight)

Frequencies of constituting significant syndromes

867

735

Proportions relative to significant syndromes

0.31

0.001

Proportions relative to all syndromes

0.172

0.001

5

Time to walk 8 ft, converted to time to walk 15 ft. Cutoff criteria according to sex and height remain the same (variable name = r7frail3_4)

Grip strength, right hand (variable name = r7gripr)

Frequencies of constituting significant syndromes

867

688

Proportions relative to significant syndromes

0.31

0.001

Proportions relative to all syndromes

0.172

0.001