Table 3 Regression coefficients of the quartiles of bone alkaline phosphatase with hearing threshold.

From: Exploring the association of Bone Alkaline Phosphatases And Hearing Loss

Variables

High-PTA

Low-PTA

β (95% CI)

P value

β (95% CI)

P value

Model 1

Q2 v.s. Q1

−0.011 (−0.038,0.015)

0.402

0.032 (0.005,0.060)

0.020

Q3 v.s. Q1

−0.011 (−0.029,0.027)

0.957

0.040 (0.012,0.069)

0.006

Q4 v.s. Q1

0.039 (0.009,0.069)

0.010

0.050 (0.020,0.080)

0.001

P for trend

<0.001

<0.001

Model 2

Q2 v.s. Q1

−0.011 (−0.036,0.016)

0.410

0.031 (0.003,0.058)

0.029

Q3 v.s. Q1

−0.001 (−0.028,0.028)

0.997

0.038 (0.009,0.067)

0.010

Q4 v.s. Q1

−0.040 (0.011,0.070)

0.008

0.049 (0.019,0.079)

0.002

P for trend

<0.001

<0.001

Model 3

Q2 v.s. Q1

−0.009 (−0.036,0.018)

0.524

0.032 (0.004,0.059)

0.024

Q3 v.s. Q1

0.001 (−0.027,0.029)

0.941

0.038 (0.009,0.067)

0.010

Q4 v.s. Q1

0.038 (0.008,0.068)

0.012

0.045 (0.004,0.075)

0.004

P for trend

<0.001

<0.001

  1. Model 1 adjust for: age, gender and race.
  2. Model 2 adjust for: age, gender, race, BMI, LDL-C and uric acid.
  3. Model 3 adjust for: age, gender, race, BMI, LDL-C, uric acid, ever told you had a stroke, tympanometry status, ear condition, DM status, present of heart disease and ototoxic status.
  4. Definition of abbreviations: ALP= bone alkaline phosphatase, BMI=Body Mass Index (kg/m2), LDL-C = low-density lipoprotein cholesterol, Low-PTA = Pure tone average at low frequencies, High-PTA= Pure tone average at high frequencies.
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