Figure 7
From: Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease
HldSe exposure on neurogenin-3 transduced human intestinal enteroids demonstrates a specificity in its activity. HldSe exposure did not lead to a loss of (A) cell viability as determined by a resazurin-based PrestoBlue assay. HldSe did enhance the secretion of (B) GLP-1 and (C) serotonin but not (D) glucagon, (E) Peptide-YY and (F) gastric inhibitory peptide (***p < 0.001, one-way ANOVA).
