Figure 3 | Scientific Reports

Figure 3

From: A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation

Figure 3

Transcriptome analysis of RFP+ and RFP− cardiomyocytes. (a) A heatmap of upregulated genes in RFP+ PSC-CMs at days 17 and 24 compared to RFP− cells. Rlog values are coded on the red-to-blue scale (higher expression, red; lower expression, blue). (b) Expressions of Myom2 in PSC-CMs at different time points (day 10, 17, 24, and 38). (c) Correlation between Myom2 expressions and RFP intensities in RFP+ PSC-CMs from day 17 to day 38. The correlation coefficient (R2) between Myom2 expression levels and RFP intensities was 0.916. (d) GO terms for molecular function identify for differentially enriched genes in RFP+ and RFP− cardiomyocytes. The x-axis represents the logarithms of the adjusted P-value. (e) Averaged gene expression of 8 selected GO terms for biological processes.

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