Table 3 Means and standard deviations from the sub-study 2.

From: Effects of ayahuasca on mental health and quality of life in naïve users: A longitudinal and cross-sectional study combination

HAM-D

Ayahuasca-naïve users (n = 40)

Long-term ayahuasca users (n = 23)

Ayahuasca-naïve users meeting criteria for psychiatric disorders (n = 18)

3.60 (5.7)

1.48 (2)*

5.61 (7.2)*

CAPE

   

  Total frequency score

63.3 (11.5)

63.1 (9.6)

68.6 (13.5)

  Total distress score

39.2 (23.8)

32.5 (17.9)

48 (26.7)*

  Positive symptoms frequency

26.8 (5.2)

28.5 (5.5)

28.7 (5.8)

  Positive symptoms distress

10 (8)

10.5 (7.5)

13 (9)

  Depression symptoms frequency

13.5 (2.9)

12.3 (2.2)

14.9 (3.3)*

  Depression symptoms distress

11.5 (6.5)

8.4 (5.2)

13.9 (6.9)*

  Negative symptoms frequency

23 (5)

22.1 (3.5)

24.9 (6.4)

  Negative symptoms distress

17.7 (11)

13.5 (7.1)

21 (12.4)*

SCL-90-R SOM

0.57 (0.56)

0.72 (0.4)

0.69 (0.6)

  O-C

0.63 (0.64)

0.62 (0.5)

0.85 (0.8)

  I-S

0.60 (0.54)

0.57 (0.5)

0.80 (0.6)

  DEP

0.58 (0.61)

0.56 (0.6)

0.81 (0.7)

  ANX

0.42 (0.43)

0.38 (0.4)

0.56 (0.5)

  HOS

0.52 (0.63)

0.38 (0.6)

0.72 (0.7)

  PHOB

0.07 (0.18)

0.18 (0.2)

0.06 (0.1)

  PAR

0.40 (0.43)

0.60 (0.6)

0.54 (0.4)

  PSY

0.23 (0.33)

0.35 (0.4)

0.30 (0.3)

  GSI

0.48 (0.43)

0.51 (0.4)

0.63 (0.4)

  PSDI

28.3 (19.3)

33 (18.8)

34 (19.4)

  PST

1.35 (0.44)

1.23 (0.3)

1.50 (0.5)

AAQ-II

19.9 (8.3)

18.6 (6.3)

23.9 (8.6)*

TCI-R-67 NS

22.4 (5.1)

22 (3.8)

21.7 (4.6)

  HA

18.7 (5.5)

17.3 (6.3)

20.1 (6.2)

  RD

29.2 (7)

28.8 (6.3)

29.6 (6.8)

  PER

25.3 (4.7)

27.5 (4.4)

26.1 (6)

  SELFD

30 (5.6)

23.1 (5.6)

29.2 (6.3)

  COOP

32 (4.3)

31.8 (4.9)

31.4 (4.4)

  ST

20.7 (7.1)

29.7 (7.9)**

21.2 (7.4)*

SF-36 PF

97.7 (5.4)

96.5 (5.5)

97.7 (6.2)

  RP

87.5 (29)

91.3 (17.8)

89.5 (30.4)

  BP

78 (25.8)

80.4 (21.5)

74.4 (26.1)

  GH

77.5 (17.3)

70.8 (13.8)

76.6 (20.9)

  VIT

62 (19.8)

62.1 (16.2)

56.9 (19.4)

  SF

81.2 (22.4)

87.5 (20)

75 (24.2)

  RE

72.1 (40)

89.8 (29)

61.1 (41.6)*

  MH

69.3 (17.6)

73.7 (19)

62.9 (19.6)

WHOQOL-Bref

17.4 (7)

24.9 (5.5)**

17.2 (8.1)*

  1. The middle column shows the differences observed between ayahuasca-naïve subjects and long-term ayahuasca users. The column on the right shows the differences found between long-term users and the ayahuasca-naïve participants who met the criteria for diagnosing psychiatric disorders.
  2. HAM-D = Hamilton Depression Rating Scale; SCL-90-R = Symptom Check-List-90-Revised; SOM = Somatizations; O-C = Obsessive-Compulsive; I-S = Interpersonal Sensitivity; DEP = Depression; ANX = Anxiety; HOS = Hostility; PHOB = Phobic anxiety; PAR = Paranoid ideation; PSY = Psychoticism; GSI = General Severity Index; PSDI = Positive Symptoms Distress Index; PST = Positive Symptoms Total; AAQ-II = Acceptance and Action Questionnaire; TCI-R-67 = Temperament and Character Inventory Revised; NS = Novelty seeking; HA = Harm voidance; RD = Reward dependence; PER = Persistence; SELFD = Self-directedness; COOP = Cooperativeness; ST = Self-transcendence; SF-36 = The Medical Outcomes Study 36-item Short-Form; PF = Physical function; RP = Role physical; BP = Bodily pain; GH = Global health; VIT = Vitality; SF = Social function; RE = Role emotional; MH = Mental health; WHOQOL = World Health Organization Quality of Life. * = < 0.05; ** = < 0.001.
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