Table 2 miRNA target gene set analysis for RFS and OS with experimentally verified miRNA gene targets sets for the 22-miRNA profile (miRNAs from the 5-miRNA profile are shown in bold).

From: MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

miRNA Gene Target Sets

Experimentally Verified Gene Target Lists

Expansive

p-value (RFS)

p-value (OS)

Restrictive

p-value (RFS)

p-value (OS)

hsa-miR-329-3p

344

0.00232

0.00552

8

0.00098

0.01705

hsa-miR-410-3p

157

0.00462

0.05839

10

0.09067

0.05576

hsa-miR-139-5p

69

0.00541

0.03526

25

0.01062

0.29243

hsa-miR-335-3p

193

0.02183

0.33236

3

0.34046

0.732

hsa-miR-487b-3p

15

0.07972

0.02288

8

0.07061

0.0044

hsa-miR-432-5p

63

0.08432

0.03707

4

0.54804

0.35184

hsa-miR-493-5p

70

0.09954

0.09239

3

0.34046

0.47078

  1. All miRNA gene target sets with significant or trending LS permutation test p-values for the expansive analysis are shown.