Table 1 IC50 value for cell viability of cells treated with HDAC11 inhibitors.

From: Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2

Cell Lines

Cell Type

HDAC11 Inhibitor

IC50 Values for MTT Assay

A549

Lung adenocarcinoma

FT234

6.594 µM

FT650

NA

FT895

4.663 µM

H1650

Lung adenocarcinoma

FT234

4.917 µM

FT650

NA

FT895

4.777 µM

Lung cancer associated fibroblasts (CAFs)

Fibroblasts

FT234

99.82 µM

FT650

NA

FT895

21.34 µM

AALE

Immortalized tracheobronchial epithelial

FT234

15.11 µM

FT650

NA

FT895

10.74 µM