Figure 5 | Scientific Reports

Figure 5

From: Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice

Figure 5

The dendrites of layer V neurons in PA-DV KI mice showed increased branching and elongation. (A) Representative images of Golgi-stained somatosensory cortex of control (+/+) and KI/KI mice at P14. Scale bar, 500 µm. (B) Magnified images of layer V neurons in the somatosensory cortex of control (+/+) and KI/KI mice. Scale bar, 50 µm. (C) The number of secondary dendrites that were branched from the primary dendrite within 80 µm of the soma. (D) The total length of the secondary dendrites. For both C and D, the cell numbers analyzed were 219 and 230 for + /+ and KI/KI mice, respectively, from three independent mice. The data are shown as the mean ± SEM and analyzed by two-tailed Student’s t-test. ****p < 0.0001.

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