Table 2 Significant association results for SNPs.

From: Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies

SNP

position

region

Allelea

Discovery sample (LMI)

Replication sample 1 (LBM)

Replication sample 2 (LBM)

Combined p

MAF

Beta

p

N

MAF

Beta

p

N

MAF

Beta

p

N

rs17817964

53794154

Intron

C/T

0.60

−0.10

9.28 × 10−4

2,207

0.60

−0.08

3.81 × 10−5

6,004

0.60

−0.15

1.84 × 10−6

38,282

5.92 × 10−12

rs7185735

53788739

Intron

A/G

0.60

−0.10

9.62 × 10−4

2,207

0.59

−0.08

3.61 × 10−5

6,004

0.60

−0.15

1.89 × 10−6

38,285

6.09 × 10−12

rs9936385

53785257

Intron

C/T

0.40

0.10

9.86 × 10−4

2,207

0.41

0.08

3.37 × 10−6

6,004

0.39

0.17

1.12 × 10−6

36,349

6.12 × 10−12

rs12149832

53808996

Intron

A/G

0.41

0.12

1.22 × 10−4

2,207

0.41

0.08

9.02 × 10−5

6,004

0.42

0.15

4.28 × 10−6

38,171

7.16 × 10−12

rs9939609

53786615

Intron

A/T

0.40

0.10

7.21 × 10−4

2,207

0.41

0.08

2.30 × 10−5

6,004

0.40

0.14

8.57 × 10−6

38,286

8.15 × 10−12

rs11075989

53785965

Intron

C/T

0.60

−0.10

9.76 × 10−4

2,207

0.59

−0.08

3.33 × 10−5

6,004

0.60

−0.15

4.79 × 10−6

38,337

9.96 × 10−12

rs11075990

53785981

Intron

A/G

0.60

−0.10

9.76 × 10−4

2,207

0.59

−0.08

3.33 × 10−5

6,004

0.60

−0.15

4.61 × 10−6

38,337

1.02 × 10−11

rs3751812

53784548

Intron

G/T

0.60

−0.10

1.06 × 10−3

2,207

0.59

−0.08

3.34 × 10−5

6,004

0.60

−0.15

4.81 × 10−6

38,325

1.10 × 10−11

rs8050136

53782363

Intron

A/C

0.40

0.10

1.10 × 10−3

2,207

0.42

0.08

2.89 × 10−5

6,004

0.40

0.14

6.64 × 10−6

38,237

1.17 × 10−11

rs9935401

53782926

Intron

A/G

0.40

0.10

1.01 × 10−3

2,207

0.41

0.08

3.53 × 10−5

6,004

0.40

0.14

5.26 × 10−6

38,338

1.28 × 10−11

rs8051591

53782840

Intron

A/G

0.60

−0.10

1.01 × 10−3

2,207

0.59

−0.08

3.54 × 10−5

6,004

0.60

−0.14

5.62 × 10−6

38,338

1.35 × 10−11

rs17817449

53779455

Intron

G/T

0.40

0.10

1.01 × 10−3

2,207

0.41

0.08

3.62 × 10−5

6,004

0.40

0.14

5.79 × 10−6

38,338

1.44 × 10−11

rs8043757

53779538

Intron

A/T

0.60

−0.10

1.01 × 10−3

2,207

0.59

−0.08

3.61 × 10−5

6,004

0.60

−0.14

5.86 × 10−6

38,338

1.45 × 10−11

rs9923233

53785286

Intron

C/G

0.40

0.10

9.86 × 10−4

2,207

0.41

0.08

3.39 × 10−5

6,004

0.41

0.14

9.59 × 10−6

38,242

1.71 × 10−11

rs17817288

53773852

Intron

A/G

0.51

−0.09

2.44 × 10−3

2,207

0.50

−0.08

3.24 × 10−5

6,004

0.51

−0.14

8.61 × 10−6

38,016

5.44 × 10−11

rs1558902

53769662

Intron

A/T

0.41

0.09

2.40 × 10−3

2,207

0.42

0.08

4.75 × 10−5

6,004

0.41

0.14

7.52 × 10−6

38,261

5.54 × 10−11

rs7202116

53787703

Intron

A/G

0.60

−0.10

9.63 × 10−4

2,207

0.59

−0.08

3.68 × 10−5

6,004

0.60

−0.16

1.87 × 10−5

28,232

5.69 × 10−11

rs1421085

53764042

Intron

C/T

0.41

0.09

2.30 × 10−3

2,207

0.42

0.08

4.87 × 10−5

6,004

0.41

0.14

7.72 × 10−6

38,254

5.73 × 10−11

rs9930506

53796553

Intron

A/G

0.56

−0.10

7.99 × 10−4

2,207

0.57

−0.07

3 × 10−4

6,004

0.56

−0.13

4.66 × 10−5

37,911

4.96 × 10−10

rs9922619

53797859

Intron

G/T

0.56

−0.10

8.76 × 10−4

2,207

0.57

−0.07

3 × 10−4

6,004

0.56

−0.13

5.48 × 10−5

38,038

7.52 × 10−10

rs9922708

53797234

Intron

C/T

0.56

−0.10

8.90 × 10−4

2,207

0.57

−0.07

3 × 10−4

6,004

0.56

−0.13

5.70 × 10−5

38,038

7.69 × 10−10

rs9932754

53796579

Intron

C/T

0.44

0.10

1.04 × 10−3

2,207

0.43

0.07

3 × 10−4

6,004

0.44

0.13

5.98 × 10−5

38,038

9.12 × 10−10

rs9930501

53796540

Intron

A/G

0.56

−0.10

1.04 × 10−3

2,207

0.57

−0.07

3 × 10−4

6,004

0.56

−0.13

6.31 × 10−5

38,037

9.62 × 10−10

rs9931494

53793267

Intron

C/G

0.58

−0.09

3.38 × 10−3

2,207

0.58

−0.07

2 × 10−4

6,004

0.58

−0.13

2.79 × 10−5

38,118

1.08 × 10−9

rs7201850

53787950

Intron

C/T

0.58

−0.09

3.37 × 10−3

2,207

0.58

−0.07

2 × 10−4

6,004

0.58

−0.13

2.89 × 10−5

38,118

1.12 × 10−9

rs9941349

53791576

Intron

C/T

0.58

−0.09

3.41 × 10−3

2,207

0.58

−0.07

2 × 10−4

6,004

0.58

−0.13

2.71 × 10−5

38,106

1.15 × 10−9

rs8044769

53805223

Intron

C/T

0.52

0.10

5.37×10−4

2,207

0.52

0.07

5 × 10−4

6,004

0.52

0.13

5.79 × 10−5

38,303

1.20 × 10−9

rs9922047

53772368

Intron

C/G

0.49

−0.08

5.85 × 10−3

2,207

0.48

−0.08

9.21 × 10−5

6,004

0.48

−0.13

6.34 × 10−5

38,164

1.37 × 10−9

rs11075987

53781249

Intron

G/T

0.51

0.09

3.09 × 10−3

2,207

0.51

0.07

2 × 10−4

6,004

0.51

0.13

3.97 × 10−5

38,185

1.69 × 10−9

  1. aThe first allele represents the minor allele of each marker.
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