Table 2 Inter-relationships of key variables, assessed via multivariable linear regression models, per SD unit higher in the exposure (adjusted for age, sex and SEP).
Models (the exposure and outcome) | Children | Adults | ||
|---|---|---|---|---|
Effect size (95% CI) | p | Effect size (95% CI) | p | |
BMI/WHtR and proposed inflammatory mediator | ||||
BMI and GlycA | 0.39 (0.33, 0.45) | <0.001 | 0.47 (0.42, 0.52) | <0.001 |
WHtR and GlycA | 0.44 (0.38, 0.49) | <0.001 | 0.53 (0.48, 0.57) | <0.001 |
BMI/WHtR and retinal vascular calibre outcomes | ||||
BMI and arteriolar calibre | −0.12 (−0.19, −0.06) | <0.001 | −0.16 (−0.21, −0.08) | <0.001 |
BMI and venular calibre | 0.03 (−0.04, 0.09) | 0.33 | 0.02 (−0.04, 0.07) | 0.58 |
WHtR and arteriolar calibre | −0.10 (−0.16, −0.06) | <0.001 | −0.16 (−0.22, −0.10) | <0.001 |
WHtR and venular calibre | 0.05 (−0.01, 0.12) | 0.08 | 0.03 (−0.03, 0.08) | 0.36 |
Proposed inflammatory mediator and retinal vascular calibre outcomes | ||||
GlycA and arteriolar calibre | −0.02 (−0.08, 0.04) | 0.52 | −0.09 (−0.15, −0.03) | <0.01 |
GlycA and venular calibre | 0.09 (0.03, 0.15) | <0.01 | 0.06 (0.00, 0.12) | 0.03 |
Proposed inflammatory mediator and retinal vascular calibre outcomes* | ||||
GlycA and arteriolar calibre | 0.03 (−0.03, 0.09) | 0.41 | −0.02 (−0.08, 0.05) | 0.59 |
GlycA and venular calibre | 0.09 (0.03, 0.16) | <0.01 | 0.07 (0.01, 0.14) | 0.03 |
