Table 2 Five SNPs showed significant association with one of the tested three cohorts either separately or/and as a pooled samples.

1

14q11.2

METTL17 (downstream to RNASE2)

C

T

AgP-Ger

1.12

0.99

1.26

0.08

AgP-NL

0.92

0.73

1.16

0.49

CP-EA-mod

1.15

1.04

1.28

0.00

CP-EA-sev

1.13

0.98

1.30

0.08

Pooled

1.12

1.05

1.19

0.37

0.04

FE

7.41E-04

CP-Ger

1.19

1.05

1.36

0.01

Pooled (all)

1.13

1.07

1.20

0.42

0.00

FE

2.84E-05

2

9p24.1

MRRF (upstream to TTLL11, downstream PTGS1)

G

A

AgP-Ger

1.19

1.00

1.42

0.05

AgP-NL

1.38

0.99

1.93

0.06

CP-EA-mod

1.27

1.09

1.48

0.00

CP-EA-sev

1.22

0.99

1.50

0.07

Pooled

1.24

1.13

1.37

0.86

0.00

FE

7.91E-06

CP-Ger

1.01

0.84

1.22

0.88

Pooled (all)

1.19

1.09

1.30

0.34

0.12

FE

5.77E-05

3

20q11.23

AL391095.1 - LBP

T

C

AgP-Ger

1.14

1.01

1.29

0.04

AgP-NL

1.25

0.98

1.58

0.07

CP-EA-mod

1.07

0.97

1.19

0.18

CP-EA-sev

1.17

1.01

1.35

0.04

Pooled

1.13

1.05

1.20

0.62

0.00

FE

5.44E-04

CP-Ger

1.01

0.88

1.15

0.92

Pooled (all)

1.10

1.04

1.17

0.42

0.00

FE

1.67E-03

4

HLA-DQH1

A

G

AgP-Ger

1.53

1.34

1.74

2.54E-10

AgP-NL

1.66

1.32

2.09

1.75E-05

Meta-AgP

1.56

1.39

1.75

0.54

0.00

FE

2.52E-14

5

HLA-DPA1

A

G

AgP-Ger

1.31

1.12

1.54

9.53E-04

AgP-NL

1.44

1.07

1.93

1.64E-02

Meta-AgP

1.34

1.16

1.54

FE

5.14E-05