Figure 1
From: First trimester PAPP-A serum levels and long-term metabolic outcome of mothers and their offspring

(Panel A) Cumulative events of hypoglycemic agents/insulin use in the years after birth according to the PAPP-A value in the first trimester of the index pregnancy. Log-rank test p = 0.080. It should be noted that cases of pre-gestational diabetes mellitus were excluded prior to analysis. (Panel B) Cumulative events of hypoglycemic agents/insulin use in the years after birth, in the subgroup without pregnancies following the index pregnancy, according to the PAPP-A value in the first trimester of the index pregnancy. Log-rank test p < 0.05. It should be noted that cases of pre-gestational diabetes mellitus were excluded prior to analysis. (Panel C) Correlation between Z scores of offspring height and maternal blood value of PAPP-A corrected MoM in the first trimester of pregnancy.