Figure 1 | Scientific Reports

Figure 1

From: Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions

Figure 1

The appearance and growth of GM rats. (a) Comparison of body size and skin phenotype at 15 weeks of age. (b) Details of the skin phenotype in Vdr-KO rats. Upper panels, X-ray images of the whole body; lower panels, H&E staining of the dorsal skin. (c) Growth curves from 6 to 15 weeks of age. WT male Wistar rats in (a) were commercially obtained from Sankyo Labo Service Corporation Inc. (Tokyo, Japan). WT rats in (b,c) were generated in-house by the mating of the heterozygotes of each strain. The values are shown as the means ± SEMs (n = 3–5 animals/group).

Back to article page