Figure 4

Each of the 5 observers is compared against a ‘consensus’ reference standard from the remaining 4 observers. In each case the scores of the observer not in the reference standard are thresholded at score values 1 and 2 to obtain two distinct operating points of sensitivity and specificity. The performance of CAD4TB v6 against the same reference standard is also illustrated in each case. Shaded areas representing 95% confidence intervals are calculated by bootstrapping.