Table 1 Comparisons of patient characteristics.
Characteristics | Unicornuate uterus | Normal uterus | Univariate analysis | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Singleton (n = 139) A | SR of twins to a singleton (n = 21) B | Twins (n = 46) C | SR of twins to a singleton (n = 82) D | Twins (n = 232) E | P (A vs. B) | P (A vs. C) | P (B vs. C) | P (D vs. B) | P (E vs. C) | |
Maternal age (years) | 29.5 ± 4.4 | 28.1 ± 2.9 | 29.2 ± 3.7 | 31.9 ± 3.7 | 29.7 ± 3.7 | |||||
≤24 | 11(7.9) | 2(9.5) | 5(10.9) | 4(4.9) | 15(6.5) | 0.255 | 0.209 | 0.614 | 0.002 | 0.680 |
25–29 | 69(49.6) | 12(57.1) | 19(41.3) | 17(20.7) | 97(41.8) | |||||
30–34 | 39(28.1) | 7(33.3) | 19(41.3) | 40(48.8) | 91(41.8) | |||||
≥35 | 20(14.4) | 0 | 3(6.5) | 21(25.6) | 23(9.9) | |||||
BMI (kg/m2) | 21.6 ± 3.8 | 21.4 ± 2.5 | 21.2 ± 2.9 | 21.2 ± 2.8 | 21.2 ± 2.6 | |||||
<18.5 | 24(17.5) | 3(14.3) | 6(13.0) | 12(14.6) | 34(14.7) | 1.000 | 0.276 | 0.693 | 0.882 | 0.874 |
18.5–23.9 | 87(63.5) | 14(66.7) | 35(76.1) | 58(70.7) | 168(72.4) | |||||
≥24 | 26(19.0) | 4(19.0) | 5(10.9) | 12(14.6) | 30(12.9) | |||||
FSH (mIU/mL) | 6.1 ± 3.5 | 5.5 ± 3.2 | 6.1 ± 1.3 | 4.9 ± 3.1 | 5.8 ± 1.7 | |||||
≤1.36 | 8(5.8) | 3(14.3) | 0 | 20(24.4) | 0 | 0.209 | 0.283 | 0.014 | 0.606 | 0.517 |
1.37–9.9 | 127(91.4) | 17(81.0) | 45(97.8) | 59(72.0) | 229(98.7) | |||||
≥10.0 | 4(2.9) | 1(4.8) | 1(2.2) | 3(3.7) | 3(1.3) | |||||
Infertility duration (years) | 4.8 ± 3.3 | 3.6 ± 2.1 | 5.0 ± 3.3 | 4.79 ± 3.12 | 5.7 ± 3.3 | |||||
≤3 | 60(43.2) | 11(52.4) | 18(39.1) | 35(42.7) | 66(28.4) | 0.235 | 0.819 | 0.175 | 0.246 | 0.271 |
4–6 | 43(30.9) | 8(38.1) | 14(30.4) | 25(30.5) | 96(41.4) | |||||
≥7 | 36(25.9) | 2(9.5) | 14(30.4) | 22(26.8) | 70(30.2) | |||||
Previous miscarriage | ||||||||||
No | 119(85.6) | 19(90.5) | 35(76.1) | 73(89.0) | 207(89.2) | 0.741 | 0.134 | 0.203 | 0.848 | 0.015 |
Yes | 20(14.4) | 2(9.5) | 11(23.9) | 9(11.0) | 25(10.8) | |||||
Transfer cycle | 1.1 ± 0.4 | 1.1 ± 0.3 | 1.2 ± 0.5 | 1.23 ± 0.61 | 1.2 ± 0.4 | |||||
1 | 121(87.1) | 19(90.5) | 41(89.1) | 68(84.0) | 200(86.2) | 1.000 | 0.711 | 1.000 | 0.452 | 0.594 |
≥2 | 18(12.9) | 2(9.5) | 5(10.9) | 13(16.0) | 32(13.8) | |||||
Number of retrieved oocytes | 8.8 ± 6.3 | 10.6 ± 5.5 | 11.3 ± 5.9 | 10.2 ± 6.6 | 9.7 ± 6.8 | |||||
≤10 | 66(47.5) | 9(42.9) | 16(34.8) | 30(36.6) | 103(44.4) | 0.692 | 0.133 | 0.526 | 0.597 | 0.229 |
>10 | 73(52.5) | 12(57.1) | 30(65.2) | 52(63.4) | 129(55.6) | |||||
EM thickness on transfer day (mm) | 12.5 ± 2.2 | 12.9 ± 2.2 | 12.2 ± 2.1 | 12.5 ± 2.2 | 12.7 ± 2.2 | |||||
≤7.9 | 1(0.7) | 0 | 0 | 0 | 1(0.4) | 1.000 | 0.851 | 0.698 | 0.860 | 0.609 |
8–14.9 | 120(86.3) | 18(85.7) | 41(89.1) | 69(84.1) | 194(83.6) | |||||
≥15 | 18(12.9) | 3(14.3) | 5(10.9) | 13(15.9) | 37(16.0) | |||||
Number of transferred embryos | ||||||||||
1 | 23(16.5) | 0 | 0 | 0 | 0 | 0.066 | 0.003 | 1.000 | 1.000 | 1.00 |
2 | 110(79.1) | 21(100.0) | 44(95.7) | 79(96.3) | 221(95.3) | |||||
3 | 6(4.3) | 0 | 2(4.3) | 3(3.7) | 11(4.7) | |||||
Infertility type | ||||||||||
Primary | 72(51.8) | 16(76.2) | 19(41.3) | 33(40.2) | 126(54.3) | 0.036 | 0.217 | 0.008 | 0.003 | 0.107 |
Secondary | 67(48.2) | 5(23.8) | 27(58.7) | 49(59.8) | 106(45.7) | |||||
Cause of infertility | ||||||||||
Male factor | 7(5.0) | 0 | 1(2.2) | 3(3.7) | 13(5.6) | 0.613 | 0.856 | 0.810 | 0.526 | 0.400 |
Female factor | 83(59.7) | 11(52.4) | 27(58.7) | 48(58.5) | 112(48.3) | |||||
Combined female and male factors | 47(33.8) | 10(47.6) | 17(37.0) | 31(37.8) | 105(45.3) | |||||
Unexplained | 2(1.4) | 0 | 1(2.2) | 0 | 2(0.9) | |||||
14-day hCG (mIU/ml) | 516.1 ± 261.6 | 1069.6 ± 264.4 | 1067.0 ± 404.3 | 967.7 ± 338.6 | 1015.5 ± 438.6 | |||||
<420 | 59(42.4) | 0 | 1(2.2) | 2 (2.4) | 14(6.0) | <0.001 | <0.001 | 1.000 | 0.202 | 0.462 |
≥420 | 80(57.6) | 21(100.0) | 45(97.8) | 80(97.6) | 218(94.0) | |||||
Insemination method | ||||||||||
IVF | 72(51.8) | 16(76.2) | 36(78.3) | 47(57.3) | 190(81.9) | 0.136 | 0.007 | 1.000 | 0.280 | <0.001 |
ICSI | 26(18.7) | 2(9.5) | 4(8.7) | 16(19.5) | 42(18.1) | |||||
IVF/ICSI | 41(29.5) | 3(14.3) | 6(13.0) | 19(23.2) | 0(0.0) |