Table 3 IC50 values of curcumin delivered via DMSO or in SEDDS to OCI-AML-2 cells. IC50 was calculated using non-linear regression model (logarithmic inhibitor vs. normalized response-variable slope).

From: Avocado-derived polyols for use as novel co-surfactants in low energy self-emulsifying microemulsions

 

DMSO (µg/mL)

SEDDS (µg/mL)

Curcumin

8.55 ± 0.10a

5.83 ± 0.19b

Curcumin + AVO

3.75 ± 0.18a

1.08 ± 0.13b

  1. Different superscript letters within each row indicate significant differences (P < 0.0001) between treatments, two-way ANOVA with Sidak’s post hoc test (n = 3).