Table 2 Collagen fibers parameters of intratumoral stroma and adjacent skin of vulvar squamous cell carcinoma (VSCC) in the labia minora and labia majora.

From: Study on collagen parameters in vulvar cancer and preneoplastic lesions by Second Harmonic Generation microscopy

Parameters

VSCC  - Labia minora

P-valor*

VSCC - Labia majora

P-valor*

Intratumoral stroma

adjacent skin

Intratumoral stroma

adjacent skin

Median (IQR)

Median (IQR)

Median (IQR)

Median (IQR)

Quantity

13.54 (13.4–14.02)

15.73 (15.6–17.1)

0.001

14.43 (13.6–15.3)

16.7 (16.1–16.4)

<0.0001

Uniformity

1.25 (1.09–1.90)

4.06 (3.94–5.89)

0.0003

2.55 (1.42–3.68)

4.68 (4.55–5.22)

0.0005

Organization

0.033 (0.006–0.054)

0.17 (0.14–0.29)

0.001

0.10 (0,02–0.19)

0.21 (0.20–0.24)

0.004

  1. IQR: interquartile; *Mann Whitney test. p < 0.05.