Table 2 The dynamics of parameter changes on the 1st day of treatment.

From: Colloidal Silicon Dioxide in Tablet form (Carbowhite) Efficacy in Patients with Acute Diarrhea: Results of Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study

Parameter

Mean value

P value

Placebo group (n = 24)

Treatment group (n = 120)

Weight, Me (IQR), kg

70.5 (65.0–84.5)

73.0 (66.5–80.5)

0.98

DBP, Me (IQR), mm Hg

77.5 (70–80)

80 (70–80)

0.45

SBP, Me (IQR), mm Hg

120 (117.5–120)

120 (117.5–120)*

0.24

\({\rm{HR}}{,}^{\overline{X}}\) ±SD, b/min

74.9 ± 3.3*

74.7 ± 3.8*

0.79

T,\({}^{\overline{X}}\) ±SD, °С

36.78 ± 0.30*

36.70 ± 0.22*

0.26

\({\rm{Acts}}{,}^{\overline{X}}\) ±SD, times

5.0 ± 1.9*

3.7 ± 2.3*

<0.001

\({\rm{Dose}}{,}^{\overline{X}}\) ±SD, tablets

13.2 ± 1.9

12.4 ± 1.2

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  1. Abbreviations: IQR – interquartile range; T – body temperature; Me – median; SBP – systolic blood pressure; DBP – diastolic blood pressure; HR – heart rate; SD – standard deviation.
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