Figure 4

Histopathology of pancreas tissue of non-diabetic and diabetic rats stained with hematoxylin and eosin (H & E) following heavy metal exposure. (a) non-diabetic control group, (b) non-diabetic arsenic (As)-treated group, (c) non-diabetic cadmium (Cd)-treated group, (d) non-diabetic manganese (Mn)-treated group, (e) non-diabetic lead (Pb)-treated group, (f) non-diabetic metal mixture (As + Cd + Mn + Pb)-treated group, (g) diabetic untreated group, (h) diabetic As-treated group, (i) diabetic Cd-treated group, (j) diabetic Mn-treated group, (k) diabetic Pb-treated group and (l) diabetic metal mixture (As + Cd + Mn + Pb)-treated group. Note: All the images represent × 20 magnification and scale bars represent 102 μm. Further, blue arrows represent vacuolation, green arrows represent cellular degeneration and black arrows represent congestion.