Table 1 Comparison of genotype frequencies of rs1695 in GSTP1 gene between oral cancer patients and healthy controls.

From: Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites

SNP ID

Gene Name

Alleles

Healthy Control Group

Oral Cancer Group

Odds ratio (95%CI)a

Genotype Frequencies

Minor allele freq

p-value (HWE)

Genotype counts

Minor allele freq

Unadjusted p-valueb

Adjusted p-valuec

n

AA

AG

GG

n

AA

AG

GG

rs1695

GSTP1

A > G

444

213

195

36

0.3

>0.05

445

332

98

15

0.14

3.1

(2.4–4.2)

0.0002d

2.4

1.7–3.2)

0.0001d

  1. aThe odds ratio was calculated for the common genotype (AA) with reference to the variant genotype (AG + GG); Dominant model.
  2. bChi-square p-value estimated by comparing genotype frequencies between cases and controls.
  3. cOdds ratio and p-value for multivariate logistic regression adjusted for age, sex and habit between cases and controls.
  4. dp-value < 0.05 is considered to be significant.