Table 2 Multivariate Binary Logistic Regression Analysis with habit-matched to identify risk genotypes associated with oral cancer in rs1695 of GSTP1 gene.

From: Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites

Habit

Genotypes

No. of Controls

No. of Cases

Adjusted OR (95% CI)

p-value

RAN only

AA

69

139

2.4 (1.5–3.9)a

0.00011

AG + GG

93

59

Reference

 

RAN + Tobacco

AA

126

195

2.4 (1.6–3.6)1

0.00011

AG + GG

84

54

Reference

 
  1. OR: odds ratio; 95% CI: 95% confidence interval; p-value <0.05 is considered to be significant.
  2. aThe Odds ratio and p-value were estimated after adjusting age and sex
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