Figure 5

GSH levels in tumor, contralateral normal-appearing brain tissue and healthy brain tissues evaluated by MRS of extracts. (A) Typical 500 MHz 1H MRS spectrum of the aqueous fraction of tumor, contralateral normal-appearing brain and healthy brain where the GSH regions are highlighted. (B) Quantification of GSH levels. 126.6 ± 16.3pmol, 42.8 ± 9.1pmol and 28.0 ± 8.0pmol per mg of wet tissue of tumor, contralateral normal-appearing brain and healthy brain respectively. Black: tumor; Striped black bar: Contralateral normal-appearing brain; Red: Healthy brain. **p < 0.01.