Figure 4 | Scientific Reports

Figure 4

From: Multiaxial Lenticular Stress-Strain Relationship of Native Myocardium is Preserved by Infarct-Induced Natural Heart Regeneration in Neonatal Mice

Figure 4

Lenticular Hydrostatic Deformation Testing. (a) Biomechanical testing configuration with mouse left ventricle (LV) wall sample mounted over a pressurizable, sealed chamber. The heart is mounted such that the LV territory supplied by the left anterior descending (LAD) coronary artery is centered over the orifice of the gasket (LAD ligation stitch, green arrow). The inflow port and pressure sensor are also labeled. (b) The LV is pressurized up to 150 mmHg, inducing lenticular deformation. (c) Tissue deformation (magenta trace) is modeled as the cap section of a sphere with radius, R (dark blue trace). The height, h, of the spherical cap is labeled. (d) Schematic illustration of lenticular hydrostatic deformation testing, created using Autodesk Fusion 360 software (https://www.autodesk.com/products/fusion-360/overview).

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