Table 2 Estimation of rates of decline in estimated glomerular filtration rate using robust regression model for the group with GSG abnormal for age.

From: Age-adjusted global glomerulosclerosis predicts renal progression more accurately in patients with IgA nephropathy

 

Model 1a

Model 2b

Model 3c

GSG

Normal for age

Reference

Reference

Reference

Abnormal for age

−1.56 (−3.11–0.01)d

−2.41 (−4.04–−0.79)e

−1.85 (−3.68–−0.03)d

  1. Note: The magnitude in rates of eGFR decline of the group with GSG abnormal for age was expressed as changes of ml/min/1.73 m2 per year compared to the group with GSG normal for age.
  2. aModel 1 was not adjusted for other variables.
  3. bModel 2 was adjusted for sex, smoking, hypertension, diabetes, age, body mass index, baseline eGFR, and baseline 24 hr urine protein.
  4. cModel 3 was adjusted for Model 2 variables plus the Oxford classification, e.g. M, E, S, T (T0 or T1–2), and C (C0 or C1-2), and immunosuppressive therapy.
  5. dP < 0.05; e P < 0.010.
  6. Abbreviation: GSG, globally sclerotic glomeruli; eGFR, estimated glomerular filtration rate.