Figure 5
From: Dietary countermeasure mitigates simulated spaceflight-induced osteopenia in mice
Differences in vertebrae compressive strength after exposure to simulated spaceflight. Mice were fed either the control diet (CD) or dried plum diet (DP), and were either irradiated with 2 Gy 137Cs (IR), hindlimb unloaded (HU), or treated with both (HU + IR). Monotonic compression testing was performed on the L4 vertebrae to obtain information about differences in maximum load (a) and vertebral stiffness (b). Stiffness was normalized to vertebral height. Representative force-displacement curves are shown for compression of the L4 vertebrae when mice were fed the CD diet (c) versus the DP diet (d). Data shown are mean + /− S.D. (n = 5–10/group). Different letters indicate p < 0.05,1-factor ANOVA with all pairs Tukey Kramer.
