Table 2 Patient and tumor characteristics by CONUT group.
Total | CONUT ≤ 2 | CONUT ≥ 3 | P | |
---|---|---|---|---|
Age | 581 | 280 | 0.003 | |
≤ 40 | 211 (24.5%) | 160 (27.5%) | 51 (18.2%) | |
> 40 | 650 (75.5%) | 421 (72.5%) | 229 (81.8%) | |
ER | 0.456 | |||
+ | 538 (62.5%) | 368 (63.3%) | 170 (60.7%) | |
− | 323 (37.5%) | 213 (36.7%) | 110 (39.3%) | |
PR | 0.505 | |||
+ | 396 (46.2%) | 264 (45.4%) | 134 (47.9%) | |
− | 465 (53.8%) | 317 (54.3%) | 146 (52.1%) | |
HER2 | 0.253 | |||
+ | 198 (23.0%) | 127 (21.9%) | 71 (25.4%) | |
− | 663 (77.0%) | 454 (78.1%) | 209 (74.6%) | |
Ki-67 status | 0.246 | |||
+ | 568 (65.2%) | 358 (63.8%) | 190 (67.9%) | |
− | 293 (34.8%) | 203 (36.2%) | 90 (32.1%) | |
pT Stage | 0.003 | |||
1 | 287 (33.3%) | 209 (37.3%) | 78 (26.0%) | |
2 | 449 (52.1%) | 283 (50.4%) | 166 (55.3%) | |
3 | 91 (10.6%) | 49 (8.7%) | 42 (14.0%) | |
4 | 34 (3.9%) | 20 (3.6%) | 14 (4.7%) | |
pN Stage | P < 0.001 | |||
0 | 370 (43.0%) | 278 (47.9%) | 92 (32.7%) | |
1 | 309 (35.9%) | 203 (35.0%) | 106 (37.7%) | |
2 | 130 (15.1%) | 69 (11.9%) | 61 (21.7%) | |
3 | 52 (6.0%) | 30 (5.2%) | 22 (7.8%) | |
Molecular subtype | 0.095 | |||
Luminal A | 223 (25.9%) | 162 (27.9%) | 61 (21.8%) | |
Luminal B | 407 (47.3%) | 262 (45.1%) | 145 (51.8%) | |
HER2-enriched | 135 (15.7%) | 87 (15.0%) | 48 (17.1%) | |
TNBC | 96 (11.1%) | 70 (12.0%) | 26 (9.3%) | |
Histological grade | 0.227 | |||
I-II | 585 (67.9%) | 387 (66.6%) | 198 (70.7%) | |
III | 276 (32.1%) | 194 (33.4%) | 82 (29.3%) | |
Surgery type | 0.041 | |||
Mastectomy | 688 (79.9%) | 453 (78%) | 235 (83.9%) | |
BCS | 173 (20.1%) | 128 (22%) | 45 (16.1%) | |
Chemotherapy | 0.057 | |||
Yes | 606 (70.4%) | 397 (68.3%) | 209 (74.6%) | |
No | 225 (29.6%) | 184 (31.7%) | 71 (25.4%) | |
Hormonal therapy | 0.233 | |||
Yes | 655 (76.1%) | 435 (74.9%) | 220 (78.6%) | |
No | 206 (26.9%) | 146 (25.1%) | 60 (21.4%) | |
Radiotherapy | 0.320 | |||
Yes | 393 (45.6%) | 121 (43.2%) | 272 (46.8%) | |
No | 468 (54.4%) | 159 (56.8%) | 309 (53.2%) | |
Target therapy | 0.114 | |||
Yes | 125 (14.5%) | 92 (15.8%) | 33 (11.8%) | |
No | 736 (85.5%) | 489 (84.2%) | 247 (88.2%) |