Figure 4

Hemodynamic changes with hand use after recovery. (a,c) Time-course curves of paired t-values of the hemodynamic response in Monkeys 1 (a) and 2 (c) after recovery of dexterous hand movements after infarction. The t-values for the paired t-test were calculated from the difference in hemodynamics during trials of left-hand and right-hand use in the session using a food well with a diameter of 10 mm. The t-values of ΔHbO and ΔHbR in each channel are drawn with red and blue lines, respectively. The horizontal dotted lines in each frame indicate levels of p = 0.0001. The horizontal axis indicates time from the onset of the retrieval movement (vertical dashed line). The locations of fNIRS optodes are shown by gray circles with probe numbers (PR). (b,d) Color-mapping of t-values onto the anatomical MR images of Monkeys 1 (b) and 2 (d). The t-values for ΔHbO around 3.5 s (for Monkey 1) and 2.0 s (for Monkey 2) after task onset are depicted. Amplitudes of t-values at most channels were maximal at these times. Arrows indicate the positions of the PMv in the left (b) and right hemispheres (d).