Figure 2 | Scientific Reports

Figure 2

From: Toward neuroprosthetic real-time communication from in silico to biological neuronal network via patterned optogenetic stimulation

Figure 2

MEA recordings, calcium imaging and video-projection of images. (A) Bright field image of the neuronal culture grown on the MEA corresponding to the area where images (stimuli) from the SNN were projected. Binary images (blue and black) were projected. The blue light (460 nm) was triggering the response of light sensitive neurons, expressing the ChR2 variant CHiEF. (B) Expression of ChR2 (left) in the same area shown in (A) The activity of the neurons was also recorded with the red calcium sensor RHOD-3 (right). (C) Two representative blue light patterns of stimulation (black and white image).

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