Figure 2 | Scientific Reports

Figure 2

From: DNA:RNA hybrid G-quadruplex formation upstream of transcription start site

Figure 2

Participation of RNA and DNA in HQ formation upstream of a T7 promoter. (a) Native gel electrophoresis showing that HQ formation (blue arrowhead) upstream of TSS required RNA and did not occur when RNA transcripts were captured by complementary DNA oligonucleotides. (b) HQ formation involved the G-tracts in DNA upstream of TSS that were protected from cleavage in DMS footprinting. N, No transcription. T, Transcribed.

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