Table 1 Combination indices (CI) for A172 and U87MG glioblastoma cells treated with the indicated concentrations of Temozolomide (TMZ) and Trametinib (Tram).
From: The limitations of targeting MEK signalling in Glioblastoma therapy
TMZ [µM] | Tram [nM] | CI [A172] | CI [U87MG] |
|---|---|---|---|
1.0 | 0.3 | n/a | 2.00473 |
1.0 | 3.0 | 418.991 | 65.3043 |
1.0 | 30.0 | 2.98444 | 0.40387 |
10.0 | 0.3 | 0.25625 | 1.47692 |
10.0 | 3.0 | 1.23495 | 4.08104 |
10.0 | 30.0 | 0.65564 | 0.47712 |
100.0 | 0.3 | 0.29330 | 0.25038 |
100.0 | 3.0 | 1.52078 | 0.45116 |
100.0 | 30.0 | 0.38133 | 0.36958 |
