Figure 2 | Scientific Reports

Figure 2

From: Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations

Figure 2

Performance of HLA target-enrichment experiments. Comparison between the median values of (A) endogenous DNA content (B) percentage of reads aligning to HLA genes (C) average HLA coverage and (D) average HLA read depth calculated across a subset of 62 aDNA samples before and after performing the HLA enrichment experiments. Significant differences between median values, as derived from Mann-Whitney test, are indicated by horizontal line and asterisks (***p < 0.001). Box plots show median, interquartile range, min-max whiskers and outliers.

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