Table 4 Histopathologic characteristics of BCC lesions.
From: Different histopathologic profiles and outcomes between sun-exposed BCC and non-sun-exposed BCC
SEBCC | NSEBCC | p-value | |
|---|---|---|---|
Lesion number (%) | 363 (90.1%) | 40 (9.9%) | |
Dimension (cm), mean ± SD | 1.10 ± 1.07 | 1.96 ± 1.52 | p = 0.002* |
Depth (mm), mean ± SD | 3.34 ± 2.42 | 3.19 ± 6.54 | p = 0.904* |
Clark level (%) | p < 0.001 | ||
I | 0 (0.0) | 0 (0.0) | |
II | 5 (0.4) | 3 (11.5) | |
III | 1 (0.4) | 4 (15.4) | |
IV | 212 (84.1) | 17 (65.4) | |
V | 34 (13.5) | 2 (7.7) | |
Margin free (%) | 258 (91.5) | 28 (90.3) | p = 0.826 |
Closest margin distance (mm), mean ± SD (range) | 2.01 ± 1.46 (0.1–9.0) | 3.77 ± 2.08 (0.5–8.0) | p < 0.001* |
High risk features n. (mean ± SD) | 1.63 ± 0.59 | 1.04 ± 0.77 | p < 0.001* |
Depth> 2 mm | 200 (62.7) | 8 (29.6) | p = 0.001 |
Clark level ≥ 4 | 247 (97.6) | 19 (73.1) | p < 0.001 |
Lesions on ear or lip (%) | 22 (6.1) | 0 (0.0) | p = 0.149 |
Perineural invasion (%) | 2 (0.8) | 0 (0.0) | p > 0.999 |
Histopathology (%) | p < 0.001 | ||
Nodular | 203 (82.2) | 16 (55.2) | |
Micronodular | 6 (2.4) | 0 (0.0) | |
Superficial | 8 (3.2) | 7 (24.1) | |
Infiltrating or mixed-infiltrating | 13 (5.3) | 0 (0.0) | |
Morpheaform | 3 (1.2) | 1 (3.4) | |
Basosquamous | 3 (1.2) | 0 (0.0) | |
Adenoid | 1 (0.4) | 0 (0.0) | |
Other | 10 (4.0) | 5 (17.2) | |
AJCC Staging (%) | p = 0.314 | ||
Stage 1 | 95 (39.1) | 14 (53.8) | |
Stage 2 | 145 (59.7) | 12 (46.2) | |
Stage 3 | 3 (1.2) | 0 (0.0) | |
