Figure 5

Distribution boxplot of the normalized expression level at each time point of Ultrasound Imaging Markers. The normalization was performed by dividing each measured value by the mean value of the whole population (treated and control) at T0, before treatment (up: Non Targeted microbubble, middle: VEGFR-1, down: FSHR). The boxplots compare placebo (red) and sunitinib (green) groups. We can see the differences are significant (*) at the 3 post-treatment initiation points (Day 7, 14 and 28) with the molecular imaging while non significant with the non targeted microbubble.