Figure 2 | Scientific Reports

Figure 2

From: Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium

Figure 2

Evaluation of entropy relative to the degree of pigmentation in hiPSC-RPE sheet in vitro. Digital photographs (a) and micrograph (b) of human induced pluripotent stem cell-derived retinal pigment epithelial (hiPSC-RPE) sheets in transwells, showing pigment spots. The sheet was used after 62 days of seeding in a transwell. Enlarged grey-scale image (c, left) corresponding to en face entropy map. Polarization-sensitive optical coherence tomography entropy map of a hiPSC-RPE sheet showing variation in entropy values (c, right). Scatter-plot of entropy vs. luminesce of grey-scale (a higher value indicates less pigmentation) in each region of interest (d). Scale bar, 50 µm.

Back to article page