Table 2 Five sets of parameters used in Fig. 2 for Model 1.

From: First-passage times and normal tissue complication probabilities in the limit of large populations

Parameter

Definition

Value

(A)

(B)

(C)

(D)

(E)

b

mitosis rate (day−1)

0.019

0.019

0.019

0.019

0.038

d

natural death rate (day−1)

0.002

0.002

0.002

0.002

0.004

h0

irradiated death rate (day−1)

0.035

0.032

0.026

0.026

0.026

M

typical population size (see text)

500

500

500

5000

500

\(\ell \)

threshold for onset of NTC

1/3

1/3

1/3

1/3

1/3

  1. These parameter sets are the same as those considered by Stocks et al.10, but we have defined separate mitosis and natural death rates to be able to analyse stochastic effects in finite populations. The ratio of mitosis and natural death was chosen as 10:1, consistent with literature5.